David Oupicky, PhD

The Oupicky Lab focuses on exploring polymers and nanoparticles for delivery of drugs and nucleic acids. We are especially interested in pharmacologically active polymers (polymeric drugs) and in delivery vectors suitable for delivery of drug/gene, drug/siRNA, and drug/miRNA combinations in the treatment of metastatic cancer and inflammatory bowel disease.


  • Ying’s paper on combination miRNA nanoparticles for the treatment of cholangiocarcinoma published in Theranostics, July 2018
  • Congratulations to Shrey Kanvinde on successful defense of his PhD dissertation on the topic of oral drug delivery to treat inflammatory bowel disease, June 2018
  • Congratulations to Yi Chen on successful defense of her PhD dissertation on the topic of renal drug delivery in acute kidney injury, May 2018
  • Ling’s paper on combined PAI-1 and CXCR4 inhibition to treat pulmonary fibrosis published in Nanomedicine NBM, May 2018
  • Ying’s review paper on chemokine targeting in metastatic cancer published in WIREs Nanomedicine and Nanobiotechnology, April 2018
  • Lee was awarded NIH F31 Fellowship from the NCI. Congratulations!, March 2018
  • Our new paper on cyclam-PEI inhibitors of CXCR4 for delivery of siVEGF published in Biomacromolecules, January 2018
  • Yi’s paper on conjugate polyplexes published in Bioconjugate Chemistry, January 2018
  • Our new paper on emulsion polyplexes published in Nano Research, December 2017
  • Our new paper on fluorinated siRNA polyplexes published in Advanced Healthcare Materials, November 2017
  • Dr. Ipek Baysal from Hacettepe University in Ankara joined the lab as a visiting faculty, October 2017
  • Johannes Bader from Ludwig-Maximilians-University of Munich joined the lab as a visiting graduate student, September 2017
  • Suthida Boonsith defended her PhD dissertation and started her faculty position at Mahidol University in Thailand. Congratulations!, August 2017
  • Prof. Oupicky appointed as a standing member of the NIH NANO study section, July 2017
  • Fei was named Presidential Graduate Fellow. Congratulations!, July 2017