David Oupicky, PhD

The Oupicky Lab focuses on exploring polymers and nanoparticles for delivery of drugs and nucleic acids. We are especially interested in pharmacologically active polymers (polymeric drugs) and in delivery vectors suitable for delivery of drug/gene, drug/siRNA, and drug/miRNA combinations in the treatment of metastatic cancer and inflammatory bowel disease.


  • Suthida Boonsith defended her PhD dissertation. Congratulations!, August 2017
  • Prof. Oupicky appointed as a standing member of the NIH NANO study section, July 2017
  • Fei was named Presidential Graduate Fellow. Congratulations!, July 2017
  • Our new paper on chloroquine-based polycations for miRNA delivery published in Macromolecular Bioscience, July 2017
  • Our new paper on chloroquine-modified hydroxyethyl starch as an anticancer polymeric drug published in Biomacromolecules, July 2017
  • Lee’s review article on the role of CXCR4 in pancreatic cancer published in Pharmacology & Therapeutics, May 2017
  • Our new paper on mesoporous silica nanoparticles for drug delivery published in Scientific Reports, April 2017
  • A joint paper with Dr. Casero on biochemical properties of polyamine prodrug nanocarriers published in PLOS One, April 2017
  • Dr. Kaikai Wang from China Pharmaceutical University joined the lab as a visiting scholar, February 2017
  • Yazhe’s paper on tumor-penetrating nanoparticles published in ACS Nano, February 2017