David Oupicky, PhD

The Oupicky Lab focuses on exploring polymers and nanoparticles for delivery of drugs and nucleic acids. We are especially interested in pharmacologically active polymers (polymeric drugs) and in delivery vectors suitable for delivery of drug/gene, drug/siRNA, and drug/miRNA combinations in the treatment of metastatic cancer and inflammatory bowel disease.


  • Our new paper on cyclam-PEI inhibitors of CXCR4 for delivery of siVEGF accepted in Biomacromolecules, January 2018
  • Yi’s paper on conjugate polyplexes accepted in Bioconjugate Chemistry, January 2018
  • Our new paper on emulsion polyplexes published in Nano Research, December 2017
  • Our new paper on fluorinated siRNA polyplexes published in Advanced Healthcare Materials, November 2017
  • Dr. Ipek Baysal from Hacettepe University in Ankara joined the lab as a visiting faculty, October 2017
  • Johannes Bader from Ludwig-Maximilians-University of Munich joined the lab as a visiting graduate student, September 2017
  • Suthida Boonsith defended her PhD dissertation and started her faculty position at Mahidol University in Thailand. Congratulations!, August 2017
  • Prof. Oupicky appointed as a standing member of the NIH NANO study section, July 2017
  • Fei was named Presidential Graduate Fellow. Congratulations!, July 2017
  • Our new paper on chloroquine-based polycations for miRNA delivery published in special issue of Macromolecular Bioscience to honor 70th birthday of Prof. Karel Ulbrich, July 2017