Our new paper on the determinants of preferential renal accumulation of synthetic polymers in acute kidney injury has been accepted for publication in the International Journal of Pharmaceutics. Congratulations to Yi and her coauthors., July 2019Weimin and Yu received UNMC Graduate Fellowships. Congratulations, July 2019Karen Pennington joined the lab as a lab manager and technologist. Welcome, July 2019Dr. Diptesh Sil joined the lab as a new postdoc. Welcome, June 2019The Oupicky lab received a new 5-year R01 from NIAAA to develop miRNA treatments of alcohol-associated liver disease, June 2019The Oupicky lab received a new grant from the Nebraska Department of Health & Human Services to develop inhalation treatments of lung cancer, June 2019Prof. Oupicky received the 2019 Outstanding Mentor of Graduate Students award, April 2019The Oupicky lab received a new 5-year R01 from the NCI to develop polyamine miRNA delivery systems in collaboration with Prof. Casero of Johns Hopkins University, March 2019Congratulations to Lee Sleightholm for successfully defending his PhD dissertation on repurposing chloroquine for pancreatic cancer treatment. Good luck in finishing the MD part of the MD/PhD program., February 2019The Oupicky lab said goodbye to Yazhe and Ying as they both moved to their postdoc positions at Yale University, February 2019Shrey’s paper on oral treatment of colitis with polymeric chloroquine published in Acta Biomaterialia, October 2018Congratulations to Ying Xie on successful defense of his PhD dissertation on the topic of miRNA delivery in metastatic cholangiocarcinoma and pancreatic cancer, October 2018The Oupicky lab received a new 5-year R01 from NIDDK to develop siRNA-based treatments of acute kidney injury, September 2018Congratulations to Fei Yu for successfully defending her PhD dissertation on the topic of polymeric chloroquine and its use in the treatment of metastatic cancer. Good luck in your new position at MD Anderson, September 2018Our new paper on reversibly stabilized fluorinated polyplexes for systemic siRNA delivery in metastatic cancer published in ACS Nano, August 2018Our new joint paper with Drs. Byrareddy and Casero on the use of polyamine analogs to inhibit Zika virus replication published in Molecular Pharmaceutics, August 2018Ying’s paper on combination miRNA nanoparticles for the treatment of cholangiocarcinoma published in Theranostics, July 2018Congratulations to Shrey Kanvinde on successful defense of his PhD dissertation on the topic of oral drug delivery to treat inflammatory bowel disease, June 2018Congratulations to Yi Chen on successful defense of her PhD dissertation on the topic of renal drug delivery in acute kidney injury, May 2018Ling’s paper on combined PAI-1 and CXCR4 inhibition to treat pulmonary fibrosis published in Nanomedicine NBM, May 2018Ying’s review paper on chemokine targeting in metastatic cancer published in WIREs Nanomedicine and Nanobiotechnology, April 2018Lee was awarded NIH F31 Fellowship from the NCI. Congratulations!, March 2018Our new paper on cyclam-PEI inhibitors of CXCR4 for delivery of siVEGF published in Biomacromolecules, January 2018Yi’s paper on conjugate polyplexes published in Bioconjugate Chemistry, January 2018Our new paper on emulsion polyplexes published in Nano Research, December 2017Our new paper on fluorinated siRNA polyplexes published in Advanced Healthcare Materials, November 2017Dr. Ipek Baysal from Hacettepe University in Ankara joined the lab as a visiting faculty, October 2017Johannes Bader from Ludwig-Maximilians-University of Munich joined the lab as a visiting graduate student, September 2017Suthida Boonsith defended her PhD dissertation and started her faculty position at Mahidol University in Thailand. Congratulations!, August 2017Prof. Oupicky appointed as a standing member of the NIH NANO study section, July 2017Fei was named Presidential Graduate Fellow. Congratulations!, July 2017Our new paper on chloroquine-based polycations for miRNA delivery published in special issue of Macromolecular Bioscience to honor 70th birthday of Prof. Karel Ulbrich, July 2017Our new paper on chloroquine-modified hydroxyethyl starch as an anticancer polymeric drug published in Biomacromolecules, July 2017Lee’s review article on the role of CXCR4 in pancreatic cancer published in Pharmacology & Therapeutics, May 2017Our new paper on mesoporous silica nanoparticles for drug delivery published in Scientific Reports, April 2017A joint paper with Dr. Casero on biochemical properties of polyamine prodrug nanocarriers published in PLOS One, April 2017Dr. Kaikai Wang from China Pharmaceutical University joined the lab as a visiting scholar, February 2017Yazhe’s paper on tumor-penetrating nanoparticles published in ACS Nano, February 2017Our joint CPU paper on fluorinated polycations for siRNA delivery published in ACS Applied Materials & Interfaces, January 2017Joseph’s paper on AMD3465 prodrug for miRNA delivery published in Molecular Pharmaceutics, January 2017Our joint paper with Dr. Casero on microRNA delivery in combination with polyamine inhibition published in the Journal of Controlled Release, January 2017Daniela Machova from the Institute of Macromolecular Chemistry in Prague joined the lab as an exchange PhD student., September 2016Yan Wang defended her PhD dissertation and moved to her new job at UCSF. Congratulations, September 2016Our first joint CPU paper on image-guided photothermal therapy published in ACS Applied Materials & Interfaces, August 2016We say goodbye to Zhenghong as he moves on to his next job at Yale University, August 2016Fei’s paper on polymeric chloroquine and its use in lung metastasis published in the Journal of Controlled Release, July 2016We received a new NIH grant to develop CXCR4-targeted treatments of cholangiocarcinoma, June 2016Fei and Lee received UNMC Fellowships. Congratulations!, June 2016Beau Alade joined the lab as a NANO-SURP student, June 2016Our joint paper with Dr. Batra’s lab on combined CXCR4 and NCOA3 inhibition in metastatic pancreatic cancer published in Biomaterials, May 2016Fei’s paper on polymeric chloroquine published in ACS Macro Letters, February 2016Ying’s paper with Dr. Mott’s lab on miRNA delivery in cholangiocarcinoma published in Molecular Pharmaceutics, February 2016Our minireview on CXCR4 in drug delivery published in Current Pharmacology Reports, January 2016Our review article on polymeric drugs published in Journal of Controlled Release. Congratulations to Jing, Fei, and Yi, September 2015Yazhe Wang joined the lab as a visiting CSC student from China Pharmaceutical University, September 2015Joseph wins a best poster award at the 13th NanoDDS conference in Seattle, September 2015Sasha Klementiev joined the lab as a summer undergrad student, June 2015The Oupicky lab received a new grant on metastatic lung cancer from the Nebraska Department of Health and Human Services, June 2015The Oupicky lab received a new NIH R21 grant to develop oral siRNA treatment of inflammatory bowel disease, May 2015The Oupicky lab received a new NIH R21 grant on HDAC-inhibiting nanoparticles for combination cancer treatment in collaboration with the lab of Dr. Stefan at UT Dallas., April 2015Our paper on siRNA delivery published in Biomaterials Science, February 2015Collaborative paper with Prof. Stefan’s lab at UT Dallas published in Polymer Chemistry, January 2015Fei Yu joined the lab as a new PhD student, January 2015Yi Chen joined the lab as a new PhD student supported by the China Scholarship Council, December 2014Our paper on the synthesis of new mono-cyclam CXCR4 polymers published in Advanced Healthcare Materials, November 2014Dr. Oupicky received the 2014 UNMC Distinguished Scientist Award, November 2014Workshop to celebrate 10 years of the Center for Drug Delivery and Nanomedicine with Samir Mitragotri, Sasha Kabanov, and Balaji Narasimhan as main speakers, November 2014Dr. Joseph Peng (a graduate from Dr. Kopecek’s lab) joined the lab as a postdoc, October 2014Ying Xie joined the lab as a new PhD student supported by the China Scholarship Council, August 2014The Oupicky lab received a new NIH R01 grant on combination drug/siRNA delivery, August 2014Our paper on self-immolative polycations published in Molecular Pharmaceutics, August 2014Lee Sleightholm joined the lab as a new MD/PhD student, July 2014Bob’s review paper on mesoporous silica published in AAPS PharmSciTech, June 2014Ibrahim Ibrahim joined the lab as a new PhD student, June 2014Yan’s paper on PEGylated polymeric Plerixafor published in Pharmaceutical Research, May 2014Our collaborative study with Prof. Asaftei group at the University of Osnabruck published in Bioconjugate Chemistry, May 2014Dr. Elena Ferrari joined the lab as a postdoc from University of Milan, Italy, April 2014Our feature article on the current status of bioreducible polycations published in Macromolecular Bioscience and featured on MaterialsViews.com, March 2014Jing’s paper on antimetastatic activity of polymeric Plerixafor published in Biomaterials, March 2014The Oupicky lab received a new grant from the Nebraska Research Initiative on development of polymeric hernia meshes, March 2014Prof. Minjie Sun joined the lab as a visiting scholar from China Pharmaceutical University, December 2013Dr. Yogesh Patil joined the lab as a postdoc from U Montpellier, France, October 2013Chao’s paper on polycation toxicity published in Biomaterials, July 2013Dr. Manju Saraswathy joined the lab as a postdoc from U Wisconsin, July 2013Shrey Kanvinde joined the lab as a PhD student, June 2013Jing’s review article on drug-nucleic acid combinations published in Journal of Controlled Release, April 2013We have moved to UNMC, March 2013Amit successfully defended his PhD dissertation. Congratulations!, February 2013
